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Anti -Skp1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011954
產(chǎn)品規(guī)格:
Applications:
IHC/IF
Species:
H/R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

Skp1 rabbit polyclonal antibody

Protein full name

S-phase kinase-associated protein 1

Synonyms

Cyclin-A/CDK2-associated protein p19, S-phase kinase-associated protein 1A, p19A, p19skp1, Skp1, Skp1a

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Skp1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, cytoplasm

Uniprot ID

Q6PEC4




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Rat

1: 1500-1: 3000

colon, heart, liver, lung




Background


SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.




Images


Immunohistochemistry of paraffin embedded rat heart using SKP1 (GB111230) at dilution of 1:1600 (400x lens)

Immunohistochemistry of paraffin embedded rat lung using SKP1 (GB111230) at dilution of 1:1600 (400x lens)

Immunofluorescence of paraffin embedded human colon using SKP1 (GB111230) at dilution of 1:1600 (400x lens)

Immunofluorescence of paraffin embedded human liver using SKP1 (GB111230) at dilution of 1:1600 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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