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Anti -DTX1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011947
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H/M/R
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

DTX1 rabbit polyclonal antibody

Protein full name

E3 ubiquitin-protein ligase DTX1

Synonyms

FXI-T1, Protein deltex-1, Deltex1, mDTX1, RING-type E3 ubiquitin transferase DTX1, Dtx1

Immunogen

Recombinant protein corresponding to Mouse DTX1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q61010



Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 200-1: 1200

brain, colon, kidney, lung, lymph node, spinal cord




Background


The Deltex homolog 1 (E3 ubiquitin-protein ligase DTX1) functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context.




Images


Immunohistochemistry of paraffin embedded human colon using deltex (GB111202) at dilution of 1:600 (400x lens)

Immunohistochemistry of paraffin embedded mouse lung using deltex (GB111202) at dilution of 1:600 (400x lens)

Immunohistochemistry of paraffin embedded mouse lymph node using deltex (GB111202) at dilution of 1:600 (400x lens)

Immunohistochemistry of paraffin embedded rat brain using deltex (GB111202) at dilution of 1:600 (400x lens)

Immunohistochemistry of paraffin embedded rat kidney using deltex (GB111202) at dilution of 1:600 (400x lens)

Immunohistochemistry of paraffin embedded rat lymph node using deltex (GB111202) at dilution of 1:600 (400x lens)

Immunofluorescence of paraffin embedded mouse spinal cord using deltex (GB111202) at dilution of 1:200 (400x lens)

Immunofluorescence of paraffin embedded rat brain using deltex (GB111202) at dilution of 1:200 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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