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Anti -Caspase-3 Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
KT012186
產(chǎn)品規(guī)格：
100ul
Applications：
IHC/IF
Species：
H/R,H/R
購(gòu)買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項(xiàng)
Product Information
|
Description |
Caspase-3 rabbit polyclonal |
|
Protein full name |
Caspase-3 |
|
Synonyms |
Casp3, CASP3, CPP32, CPP32B, SCA-1, Caspase 3 |
|
Immunogen |
Recombinant protein corresponding to Mouse Caspase3 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Uniprot ID |
P42574, P70677, P55213 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human, Rat |
1: 100-1: 200 |
breast cancer, liver cancer, colon cancer |
|
IF |
Human, Rat |
1: 100-1: 200 |
breast cancer, liver cancer, colon cancer |
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes.
Images
|
Immunohistochemistry analysis of paraffin-embedded human breast cancer using Caspase-3 (GB11009-1) at dilution of 1: 200 |
|
Immunohistochemistry analysis of paraffin-embedded human liver cancer using Caspase-3 (GB11009-1) at dilution of 1: 200 |
|
Immunohistochemistry analysis of paraffin-embedded human colon cancer using Caspase-3 (GB11009-1) at dilution of 1: 200 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室