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Anti -MCK10/NEP Rabbit pAb

價格: 在線咨詢
貨號:
KT012002
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
H
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

MCK10 rabbit polyclonal antibody

Protein full name

Epithelial discoidin domain-containing receptor 1

Synonyms

Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, CAK, EDDR1, NEP, NTRK4, PTK3A, MCK-10, CD167a, DDR1, RTK6, TRKE

Immunogen

KLH conjugated Synthetic peptide corresponding to Human MCK10

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Secreted

Uniprot ID

Q08345




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human

1:400-1:1000

colon, colon cancer, esophagus, ovarian cancer




Background


This protein belongs to a subfamily of tyrosine kinase receptors. The Tyrosine kinase functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases.




Images


Immunohistochemistry of paraffin embedded human colon using DDR1 (GB111290) at dilution of 1:450 (400x lens)

Immunohistochemistry of paraffin embedded human colon cancer using DDR1 (GB111290) at dilution of 1:450 (400x lens)

Immunofluorescence of paraffin embedded human colon cancer using DDR1 (GB111290) at dilution of 1:400 (400x lens)

Immunofluorescence of paraffin embedded human esophagus using DDR1 (GB111290) at dilution of 1:400 (400x lens)

Immunofluorescence of paraffin embedded human ovarian cancer using DDR1 (GB111290) at dilution of 1:400 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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