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Anti -Dopamine Transporter Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012000
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
MR
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

Dopamine Transporter rabbit polyclonal antibody

Protein full name

Sodium-dependent dopamine transporter

Synonyms

DA transporter, DAT, Solute carrier family 6 member 3, Slc6a3, Dat, Dat1

Immunogen

Recombinant protein corresponding to Mouse Dopamine Transporter

Isotype

IgG

Purity

Affinity purification

Predicted MW.

69 kDa

Observed MW.

69 kDa

Uniprot ID

Q61327, P23977




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

brain, cortex, hippocampus, cerebellum




Background


DAT1, also known as SLC6A3 and Sodium-dependent dopamine transporter, is a sodium and chloride-dependent dopamine transporter belonging to the solute carrier family 6. Dopamine transporters are distributed widely across the brain in regions with high dopaminergic activity, such as the striatum and substantia nigra. These transporters effectively provide fast acting clearance of dopamine, adrenalin and noradrenalin from the synaptic cleft, thus terminating the neurotransmitter signal. DATs have been found to interact with PRKCABP, TGFB1I1, SLC18A2 and the N-terminus of SYNGR3. DATs are also the target proteins for psychomotor stimulants such as amphetamines and cocaine. Research has implicated DATs as useful markers in detecting depression, schizophrenia, Parkinson's disease and drug abuse.




Images


Picture 1.png

Western blot analysis of SLC6A3 (GB111215) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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