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Anti -GRP94 Rabbit pAb

價格: 在線咨詢
貨號:
KT011917
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
HMR
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

GRP94 rabbit polyclonal antibody

Protein full name

Endoplasmin

Synonyms

94 kDa glucose-regulated protein, GRP-94, ERp99, Heat shock protein 90 kDa beta member 1, Polymorphic tumor rejection antigen 1, Tumor rejection antigen gp96, Hsp90b1, GRP94, Tra-1, Tra1

Immunogen

Recombinant protein corresponding to Mouse GRP94

Isotype

IgG

Purity

Affinity purification

Predicted MW.

92 kDa

Observed MW.

100 kDa

Uniprot ID

P14625, P08113, Q66HD0




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

lung, brain




Background


GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.




Images


Picture 1.png

Western blot analysis of GRP94 (GB111280) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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