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Anti -MEK2 Rabbit pAb
價格：
在線咨詢
貨號：
KT012258
產(chǎn)品規(guī)格：
100ul
Applications：
WB|IHC/IF
Species：
H/M/R,M/R
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項
Product Information
|
Description |
MEK2 rabbit polyclonal antibody |
|
Protein full name |
Dual specificity mitogen-activated protein kinase kinase 2 |
|
Synonyms |
MAP kinase kinase 2, Prkmk2 ,Mek2, Mkk2, Map2k2, ERK activator kinase 2, MAPK/ERK kinase 2, MAPKK 2, PRKMK 2, PRKMK2 V |
|
Immunogen |
Recombinant protein corresponding to Mouse MEK2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Predicted MW. |
44 kDa |
|
Observed MW. |
48 kDa |
|
Uniprot ID |
P36507, Q63932, P36506 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung, brain |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 2000 |
brain, lung, spleen |
Background
MAP kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax.
Images
|
Western blot analysis of MEK2 at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded mouse brain using MEK2 at dilution of 1: 2000 (350x lens) |
|
Immunohistochemistry of paraffin embedded mouse brain using MEK2 at dilution of 1: 2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat brain using MEK2 at dilution of 1: 2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat lung using MEK2 at dilution of 1: 2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat spleen using MEK2 at dilution of 1: 2000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室