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Anti -P-NFkBp65 Rabbit pAb

價格: 在線咨詢
貨號:
KT012210
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H,M,R
購買數(shù)量:
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Product Information


Description

NF-κB p65 (phospho S536) rabbit polyclonal antibody

Protein full name

Transcription factor p65

Synonyms

RELA, NFKB3, p65, RELA proto-oncogene, NF-kB subunit

Immunogen

KLH conjugated Synthetic peptide corresponding to human NF-κB p65 around the phosphorylation site of Serine 536

Isotype

IgG

Purity

Affinity purification

Predicted MW.

65 kDa

Observed MW.

65KDa

Uniprot ID

Q04206,Q04207



Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 600-1: 1000

lung, spleen, liver



Background


NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.




Images



Picture 1.png

Western blot analysis of P-NFkBp65 (GB11142-1) at dilution of 1: 600




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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