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Anti -TANK/TRAF2 Rabbit pAb
價格：
在線咨詢
貨號：
KT012185
產(chǎn)品規(guī)格：
Applications：
WB | IHC | IF
Species：
M,R/H
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項
Product Information
|
Description |
TANK/TRAF2 rabbit polyclonal antibody |
|
Protein full name |
TRAF family member-associated NF-kappa-B activator |
|
Synonyms |
TRAF-interacting protein, I-TRAF, Tank, Itraf |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse TRAF2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Predicted MW. |
51 kDa |
|
Observed MW. |
45 kDa |
|
Uniprot ID |
Q92844, P70347 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, heart |
|
IHC/IF |
Human |
1: 500-1: 1000 |
colon cancer, kidney, liver cancer, lung |
Background
Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.
Images
|
|
Western blot analysis of ITRAF (GB112338) at dilution of 1: 500 |
|
Immunofluorescence of paraffin embedded human colon cancer using ITRAF (GB112338) at dilution of 1: 600 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human kidney using ITRAF (GB112338) at dilution of 1: 600 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human liver cancer using ITRAF (GB112338) at dilution of 1: 600 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human lung using ITRAF (GB112338) at dilution of 1: 600 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室