Recombinant protein corresponding to Mouse Cyclin A1
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cytoplasm, Nucleus
Uniprot ID
Q61456
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Mouse, Rat
1: 400-1: 800
testis
Background
The
critical role that the family of regulatory proteins known as cyclins
play in eukaryotic cell cycle regulation is well established. The
best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34
kinase, the active component of maturing promoting factor. Cyclin A
accumulates prior to cyclin B in the cell cycle, appears to be involved
in control of S phase and has been shown to associate with
cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been
implicated in cell transformation and is found in complexes with E1A,
transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A
second form of cyclin A, named cyclin A1 because of its high sequence
homology to Xenopus cyclin A1, is most highly expressed in germ cells.
Images
Immunohistochemistry of paraffin embedded mouse testis using CCNA1 (GB111921) at dilution of 1:400 (300x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .