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Anti -Myelin Basic Protein Rabbit pAb

價格: 在線咨詢
貨號:
KT011601
產品規(guī)格:
100 μL
Applications:
WB | IHC | IF
Species:
M,R/M,R
購買數(shù)量:
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產品詳情 操作說明 注意事項

Product Information


Description

Myelin Basic Protein rabbit polyclonal antibody

Protein full name

Myelin Basic Protein

Synonyms

MBP, entrez:4155, myelin basic protein

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Myelin Basic Protein

Isotype

IgG

Purity

Affinity purification

Subcellular location

Myelin membrane, Cytoplasmic side of myelin

Predicted MW.

27 kDa

Observed MW.

17/20 kDa

Uniprot ID

P04370, P02688



Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1:500-1:1000

brain

IHC/IF

Mouse, Rat

1:300-1:600

brain



Background


The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined to optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function.




Images




Western blot analysis of Myelin Basic Protein (GB11226) at dilution of 1: 500

Immunofluorescence of paraffin embedded mouse brain using MBP (GB11226) at dilution of 1: 300 (400x lens)


Immunofluorescence of paraffin embedded rat brain using MBP (GB11226) at dilution of 1: 300 (400x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.




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