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Anti -NK-1R Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011499

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

M,R

品牌：

萬(wàn)物

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產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	NK-1R rabbit polyclonal antibody
Protein full name	Substance-P receptor
Synonyms	Tacr1, TACR1, NK1R, NKIR, SPR, TAC1R, Tachykinin receptor 1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TACR1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	46 kDa
Observed MW.	46 kDa
Uniprot ID	P25103, P30548, P14600

Applications

Applications

Species

Dilution

Positive Tissue

Mouse, Rat

1: 500-1: 1000

brain, heart,

spinal cord

Background

The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. It is probably associated with G proteins that activate a phosphatidylinositol calcium second messenger system. The endogenous ligand for this receptor is Substance P. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. The binding of SP to the NK1 receptor has been associated with the transmission of stress signals and pain, the contraction of smooth muscles and inflammation.

Images

Western blot analysis of TACR1 (GB11759) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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