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Anti -GABA A Receptor alpha 1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011489

產(chǎn)品規(guī)格：

100 μL

Applications：

WB | IHC | IF

Species：

H,M,R | H,M,R

品牌：

萬物

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	GABA A Receptor alpha 1 rabbit polyclonal antibody
Protein full name	Gamma-aminobutyric acid type A receptor subunit alpha1
Synonyms	ECA4, EJM, GABA A receptor alpha 1, GABAA receptor alpha 1, GABRA1
Immunogen	Recombinant protein corresponding to Mouse GABA A Receptor alpha 1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Membrane, Secreted
Predicted MW.	52 kDa
Observed MW.	52 kDa
Uniprot ID	P62812

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1500	cerebellum, hippocampus, brain
IHC/IF	Human, Mouse, Rat	1: 300-1: 600	cerebellum, brain

Background

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.

Images

	Western blot analysis of GABRA1 (GB113973) at dilution of 1: 1000
	Immunohistochemistry of paraffin embedded mouse brain using GABRA1 (GB113973) at dilution of 1: 300 (200x lens)
	Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB113973) at dilution of 1: 300 (200x lens)
	Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB113973) at dilution of 1: 400 (200x lens)
	Immunohistochemistry of paraffin embedded mouse cerebellum using GABRA1 (GB113973) at dilution of 1: 300 (200x lens)
	Immunohistochemistry of paraffin embedded rat cerebellum using GABRA1 (GB113973) at dilution of 1: 300 (200x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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