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Anti -TCPTP Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101938
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

TCPTP rabbit polyclonal

Protein full name

Tyrosine-protein phosphatase non-receptor type 2

Synonyms

Protein-tyrosine phosphatase PTP-2, MPTP, Ptpn2, Ptpt

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse TCPTP

Isotype

IgG

Purity

Affinity purification

Predicted MW.

47 kDa

Observed MW.

47 kDa

Uniprot ID

P17706, Q06180




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse

1: 500-1: 1000

ovary




Background


The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported.




Images


Western blot analysis of TCPTP (GB111126) at dilution of 1: 1000
Lane 1: Jurkat cell lysate
Lane 2:A549 cell lysate
Lane 3:K562 cell lysate
Lane 4: Mouse ovary tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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