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Anti -TNF Receptor II Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101668
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

TNF Receptor II rabbit polyclonal

Protein full name

Tumor necrosis factor receptor superfamily member 1B

Synonyms

Tumor necrosis factor receptor 2, TNFR2, p75, Tumor necrosis factor receptor type II, TNFRII, p80 TNF-alpha receptor, CD120b, Etanercept, TBP-2, TBPII, TNFRSF1B, TNFBR

Immunogen

KLH conjugated Synthetic peptide corresponding to Human TNF Receptor II

Isotype

IgG

Purity

Affinity purification

Predicted MW.

48 kDa

Observed MW.

73 kDa

Uniprot ID

P20333




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

Jurkat, A549




Background


The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.




Images


image.png

Western blot analysis of TNF Receptor II (GB111013) at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: A549 cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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