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產品詳情
操作說明
注意事項
Product Information
| Description |
Fas Ligand rabbit polyclonal |
| Protein full name |
Tumor necrosis factor ligand superfamily member 6 |
|
Synonyms |
ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6 |
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse FASL |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | |
| Uniprot ID |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse, Rat | 1: 500-1: 3000 |
Appendix, spleen, Thymus, liver |
| IF | Mouse, Rat |
1: 1500- 1: 3000 |
small intestine, thymus, lung |
Background
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Images
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Immunohistochemistry analysis of paraffin-embedded human appendix using FasL (GB11090-1) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse Immunized spleen using FasL (GB11090-1) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse Immunized thymus using FasL (GB11090-1) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded rat liver using FasL (GB11090-1) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded rat spleen using FasL (GB11090-1) at dilution of 1:1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse small intestine using FasL(GB11090-1) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using FasL(GB11090-1) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat lung using FasL(GB11090-1) at dilution of 1: 3000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室