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Anti -NDP Rabbit pAb

價格: 在線咨詢
貨號:
KT012223
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

NDP rabbit polyclonal antibody

Protein full name

Norrin

Synonyms

Norrie disease protein homolog, Ndp, Ndph, FEVR, EVR2, X linked exudative vitreoretinopathy 2 protein

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse NDP

Isotype

IgG

Purity

Affinity purification

Predicted MW.

15 kDa

Observed MW.

15 kDa

Uniprot ID

P48744




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, testis, liver



Background


NDP, also named as EVR2, ND and Norrin, is a secreted regulatory protein that remains tightly associated with the extracellular matrix. Mutations in the NDP gene are associated with the Norrie disease. Signaling induced by the protein NDP regulates vascular development of vertebrate retina and controls important blood vessels in the ear. It binds with high affinity to Frizzled 4, and Frizzled 4 knockout mice exhibit abnormal vascular development of the retina.




Images


Picture 1.png

Western blot analysis of Ndp (GB112642) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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