服務(wù)熱線
400-1016-218
聯(lián)系方式
- 手機(jī)：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國家大學(xué)科技園A401室
Anti -Topoisomerase III alpha Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
KT012130
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
H
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項(xiàng)
Product Information
|
Description |
Topoisomerase III alpha rabbit polyclonal antibody |
|
Protein full name |
DNA topoisomerase 3-alpha |
|
Synonyms |
DNA topoisomerase III alpha, TOP3A, TOP3, ZGRF7, topo III-alpha, zinc finger, GRF-type containing 7, topoisomerase III alpha |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Topoisomerase III alpha |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
112 kDa |
|
Observed MW. |
112 kDa |
|
Uniprot ID |
Q13472 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human |
1: 500-1: 1000 |
HeLa, HEK293, K562 |
Background
DNA topoisomerase 3-alpha (TOP3A) is an essential component of the RMI complex, a complex involves in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. It releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils.
Images
|
|
Western blot analysis of TOP3A (GB111889) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
凡合肥萬物生物科技有限公司銷售的產(chǎn)品均有嚴(yán)格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問，請于收貨之日起七日內(nèi)向我公司總部或當(dāng)?shù)剞k事處提出，并請保證該產(chǎn)品，以備本公司進(jìn)行核對檢驗(yàn)。如果發(fā)現(xiàn)有質(zhì)量問題，請于收貨后一月內(nèi)保留產(chǎn)品50%以上的量，以便本公司回收產(chǎn)品進(jìn)行質(zhì)檢，確認(rèn)產(chǎn)品質(zhì)量。如逾期，則視為已經(jīng)對本公司產(chǎn)品進(jìn)行驗(yàn)收。 聲明：如發(fā)生產(chǎn)品索賠事宜，本公司僅在產(chǎn)品價(jià)格范圍內(nèi)酌情賠償，恕不接受超出產(chǎn)品價(jià)格范圍之賠償?？蛻粼谑褂眠^程中有任何技術(shù)問題可以撥打技術(shù)售后服務(wù)電話我們隨時(shí)給予解答。
合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國家大學(xué)科技園A401室