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ti -Tyrosine Hydroxylase Mouse mAb
價格：
在線咨詢
貨號：
KT011753
產(chǎn)品規(guī)格：
100 μL
Applications：
IHC/IF
Species：
M/R
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項(xiàng)
Product Information
|
Description |
Tyrosine Hydroxylase mouse monoclonal antibody |
|
Protein full name |
Tyrosine 3-monooxygenase |
|
Synonyms |
TH, Th, DYT14, DYT5b, TYH, tyrosine hydroxylase, Tyrosine hydroxylase |
|
Immunogen |
Recombinant protein corresponding to Mouse Tyrosine Hydroxylase |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Axon |
|
Uniprot ID |
P24529,P04177 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 3000 |
brain, corpus striatum, substantia nigra |
Background
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). It does so using molecular oxygen(O2), as well as iron (Fe2+) and tetrahydrobiopterin as cofactors. L-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine(adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines. In humans, tyrosine hydroxylase is encoded by the TH gene,and the enzyme is present in the central nervous system (CNS), peripheral sympathetic neurons and the adrenal medulla.Tyrosine hydroxylase, phenylalanine hydroxylase and tryptophan hydroxylase together make up the family of aromatic amino acid hydroxylases(AAAHs).
Images
|
|
Immunohistochemistry of paraffin embedded mouse brain using TH (GB12181) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using TH (GB12181) at dilution of 1: 1500 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse corpus striatum using TH (GB12181) at dilution of 1: 500 (400x lens) |
|
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Immunofluorescence of paraffin embedded mouse substantia nigra using TH (GB12181) at dilution of 1: 500 (400x lens) |
|
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Immunofluorescence of paraffin embedded rat substantia nigra using TH (GB12181) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室