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Anti -LIMK1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011722
產品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
H/M/R
購買數量:
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產品詳情 操作說明 注意事項

Product Information


Description

LIMK1 rabbit polyclonal antibody

Protein full name

LIM domain kinase 1

Synonyms

LIMK1, KIZ-1, LIM motif-containing protein kinase

Immunogen

Recombinant protein corresponding to Mouse LIMK1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

P53668, P53669




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 750-1: 4000

breast cancer, lung, spinal cord, testis




Background


LIMK1, a member of the Ser/Thr protein kinase family, may be a component of an intracellular signaling pathway and may be involved in brain development. It phosphorylates and inactivates the actin binding/depolymerizing factor cofilin and induces actin cytoskeletal changes. The LIM domain interacts with the cytoplasmic domain of NRG1, and this cytoplasmic protein also binds ROCK1, which phosphorylates LIMK1 on serine and/or threonine residues. Highest expression occurs in both adult and fetal nervous systems.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded mouse lung using Limk (GB11994) at dilution of 1:2000 (250x lens)

Picture 2.png Immunohistochemistry of paraffin embedded rat testis using Limk (GB11994) at dilution of 1:2000 (200x lens)
Picture 3.png Immunohistochemistry of paraffin embedded rat lung using Limk (GB11994) at dilution of 1:2000 (250x lens)
Picture 4.png Immunofluorescence of paraffin embedded human breast cancer using Limk (GB11994) at dilution of 1:1500 (250x lens)
Picture 5.png

Immunofluorescence of paraffin embedded mouse spinal cord using Limk (GB11994) at dilution of 1:1500 (300x lens)

Picture 6.png

Immunofluorescence of paraffin embedded rat testis using Limk (GB11994) at dilution of 1:1500 (200x lens)

Picture 7.png

Immunofluorescence of paraffin embedded rat lung using Limk (GB11994) at dilution of 1:1500 (250x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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