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產品詳情
操作說明
注意事項
Product Information
|
Description |
TLR4 mouse monoclonal |
|
Protein full name |
Toll-like receptor 4 |
|
Synonyms |
TLR4, ARMD10, CD284, TLR-4, TOLL, toll like receptor 4 |
|
Immunogen |
Recombinant protein corresponding to Mouse TLR4 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
IHC |
Mouse, Rat |
1: 500-1: 1000 |
spleen |
|
IF |
Mouse, Rat |
1: 500-1: 1000 |
spleen |
Background
TLR4 is a transmembrane protein, member of the toll-like receptor family, which belongs to the pattern recognition receptor (PRR) family. Its activation leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system.It is most well known for recognizinglipopolysaccharide (LPS), a component present in many Gram-negative bacteria (e.g. Neisseria spp.) and selectGram-positive bacteria. Its ligands also include several viral proteins, polysaccharide, and a variety of endogenous proteins such as low-density lipoprotein, beta-defensins, and heat shock protein.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using TLR4 (GB12186) at dilution of 1:1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat spleen using TLR4 (GB12186) at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室