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Anti -TLR2 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101757
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

TLR2 rabbit polyclonal

Protein full name

Toll-like receptor 2

Synonyms

TLR2, CD282, TIL4, toll like receptor 2, Toll/interleukin receptor like protein 4, TIL4

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse TLR2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane

Uniprot ID

O60603, Q9QUN7




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse

1: 500-1: 1000

ovarian cancer, appendix, liver, lung

IF

Human, Mouse

1: 500-1: 1000

tonsil, cervical cancer




Background


TLR2 is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities, while the various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-κB. In the intestine, TLR2 regulates the expression of CYP1A1, which is a key enzyme in detoxication of carcinogenic polycyclic aromatic hydrocarbons such as benzo(a)pyrene.




Images


Immunohistochemistry analysis of paraffin-embedded human ovarian cancer  using TLR2 (GB113378) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human appendix using 

TLR2 (GB113378) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse liver with LPS treated for 6h using TLR2 (GB113378) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse lung with LPS treated for 12h using TLR2 (GB113378) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human cervical cancer using TLR2 (GB113378) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human tonsil using 

TLR2 (GB113378) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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