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Anti -TSLP Rabbit pAb

價格: 在線咨詢
貨號:
DRF101657
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

TSLP rabbit polyclonal

Protein full name

Thymic stromal lymphopoietin

Synonyms

Thymic stroma-derived lymphopoietin, Tslp, TSLP protein, thymic stromal lymphopoietin

Immunogen

Recombinantproteincorrespondingto Mouse TSLP

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

Q9JIE6




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 500-1: 1500

lung, brain, skin, heart

IF

Mouse, Rat

1: 500-1: 1000

prostate, lung




Background

TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c ( ) dendritic cells, naive CD4 ( ), and CD8 ( ) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 ( ) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis.




Images



Immunohistochemistry analysis of paraffin-embedded mouse lung using

TSLP(GB111664) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded rat lung using

TSLP(GB111664) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded mouse brain using

TSLP(GB111664) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded rat brain using

TSLP(GB111664) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded mouse skin using

TSLP(GB111664) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded rat skin using

TSLP(GB111664) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded rat skin using

TSLP(GB111664) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded rat heart using

TSLP(GB111664) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse prostate using

TSLP (GB111664) at dilution of 1: 650

Immunofluorescent analysis of paraformaldehyde-fixed rat lung using

TSLP (GB111664) at dilution of 1: 650




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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